Abpred


The protein-sol abpred software will take a single amino acid sequence for a Fv and calculate the predicted performance on 12 biophysical platforms, using machine learning algorithms trained on experimental data from Jain et al 2018, as described here.


Please enter a single sequence of single letter amino acid codes in the FASTA format.


Submit protein VHVL sequence
> alirocumab
EVQLVESGGGLVQPGGSLRLSCAASGFTFNNYAMNWVRQAPGKGLDWVSTISGSGGTTNYADSVKGRFIISRDSSKHTLYLQMNSLRAEDTAVYYCAKDSNWGNFDLWGRGTLVTVSSDIVMTQSPDSLAVSLGERATINCKSSQSVLYRSNNRNFLGWYQQKPGQPPNLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYTTPYTFGQGTKLEIK




Example

alirocumab


Citation

Hebditch M and Warwicker J.
Charge and hydrophobicity are key features in sequence-trained machine learning models for predicting the biophysical properties of clinical-stage antibodies
PeerJ (2019)